## Courses offered for the PhD

### Physics Courses

Introduction to probability theory and data treatment (Prof. Adriano Filipponi)

- One dimensional random variables, probability densities and characteristic functions.
- Weak convergence of sequences of random variables.
- The law of large numbers and the central limit theorem.
- Examples and applications where the requirements for the central limit theorem are not satisfied: Log-normal, Lorentzian and non homogeneous

Poisson process. - Multi-dimensional random variables, marginal distributions and correlation.
- The multi-dimensional Gauss distribution.
- Bayes’ theorem and Bayesian approaches.
- Prior parameter distribution, likelihood function and normalization.
- Elementary and non-elementary examples of Bayesian parameter estimates.
- Theleast-square empirical procedures as a special case of the Bayesian formalism.
- Computational approaches to random number generation.

The theory of Synchrotron Radiation and applied aspects (Prof. Adriano Filipponi)

### Chemistry Courses

Asymmetric organocatalysis (Prof. Armando Carlone)

- Introduction to organocatalysis - birth, history, first steps
- Various types of organocatalysts and activations
- Catalysis via enamine
- Catalysis via iminium ion
- Stereoselective activation/control via hydrogen bonding and steric encumbrance.
- Primary amines to activate ketones.
- Enamine/iminium ion catalytic cycle - similarities and domino reactions phosphoric acids, ACDC
- Tertiary amines and PTCs
- Thioureas - bifunctional
- Industrial synthesis examples: letermovir, TV-4507

Host-guest systems (Prof. Luisa Giansanti)

Photocatalysis (Prof. Andrea Baschieri)

Safety standards for synthetic and industrial chemists (Prof. Armando Carlone)

Patents, literature and bibliographic resources (Prof. Armando Carlone)